Like most 'procedures' in the beauty industry, they are generally a discovered cosmetic side effect from genuine medical treatment for certain conditions.
Botox is botulism used under strict medical supervision, until someone realised a side effect was the freezing of muscles, and the rest is history.
I have regular Caci treatment, which lifts and firms the facial muscles. This treatment originated in its medical treatment for Bell's palsy.
I have Lupus which gives a weakened immune system, so I wouldn't even consider putting a toxic bacterium into my system, and particularly by someone who just pitches up at a Salon with a briefcase !
These drugs should be left where they are - in a hospital, to do the job they were manufactured for, like treating Vienna's sister.
Re: Amanda Holden, Nicole Kidman (have you seen HER lately), Carole Vorderman and the rest, I ask, "at what stage do you stop ?" because how grotesque will they look in their 70's and 80's with wrinkled throats/aged gimlet eyes/scrawny hands with stretched skin across the face.
I saw Joan Collins on the tv the other day. Despite cries of 'how glamorous' she looks at 85, all I saw was a wig wearing woman (nothing wrong with that), but her wrinkle free cheeks were sucked in and she could barely speak - her teeth seemed too big for her mouth, so what's going on ?????